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Synthetic arabinomannans – A novel weapon against the century old mycobacterial threat

Considered as mankind’s greatest killer, Mycobacterium tuberculosis, the causative agent of tuberculosis, has indeed become one group of bacteria which has challenged microbiologists and medical researchers for decades. Since the discovery of Mycobacterium tuberculosis in 1882, many scientists and researchers have employed different strategies to handle and treat mycobacterial infections. Longtreatment regime, the emergence of multiple drug resistance and chronic infections are the serious challenges associated with tuberculosis control. Now scientists from the Indian Institute of Science (IISc) Bangalore have tried out an interdisciplinary approach for fighting these killer bacteria.

Life, the Universe and Everything!

Scientists estimate that our Solar System is 4.567 billion years old. But, have you ever wondered how it was formed? How did the planets take shape from the initial gas and dust of the solar nebula and eventually, how did life evolve on Earth? What processes shaped the initial evolution of our Solar System? These fundamental questions drive Prof. Ramananda Chakrabarti and the researchers in his lab at the Center for Earth Sciences, Indian Institute of Science, Bangalore, to study rocks on Earth and from space.

Researchers Develop Automation Tools to Help Treatment of Tumors

Tumors are often linked to cancer when they become malignant and start to spread. Doctors and researchers throughout the world are continuously seeking better ways to diagnose and treat tumors early on, thus preventing severe damage. In a rare interdisciplinary study, engineers from the Indian Institute of Science, Bangalore, have stepped up to help doctors in treating tumors. Prof. Radhakant Padhi from the Department of Aerospace Engineering and his team has designed an automation tool for slow and controlled drug release. It is an intelligent feedback algorithm that can be embedded in a micro-controller and effective in treating solid tumors with minimal side effects.

Yeasts on a protein diet: Scientists decode the mechanism behind this

Many organisms, including yeast, obtain Carbon and energy from carbohydrates and Nitrogen from other nutrients like amino acids. But some types of yeast, like Pichia pastoris, can use amino acids not only as sources of Nitrogen, but also as sources of Carbon too finds a new study at the Indian Institute of Science, Bangalore. The team, consisting of Mr. Umakant Sahu and Prof. P N Rangarajan from the Department of Biochemistry, have studied the mechanism behind how P. pastoris can grow happily in a medium that does not contain glucose but only amino acids like glutamate, aspartate, proline, etc.

Scientists design better techniques to grow crystals that imitate the hues of Nature

The vivid and myriad colours of the natural world captivate our eyes and benefit life on earth. Learning how nature colours its palette advances our understanding of the world around us and hence scientists ubiquitously are trying to imitate designs inspired by nature, to fabricate better devices. Now, a collaborative study between researchers at the Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Bengaluru, and the Indian Institute of Science (IISc), Bengaluru, has proposed a novel technique to build better display devices that imitate naturally occurring colours.

Professor Praveen Kumar - A materials scientist with an eye for detail

Dropped your mobile phone? You may soon stop worrying about it, thanks to the newly discovered phenomena related to carbon nanotube foam used as a shock-absorbent material in mobile phones. As a material scientist, Prof. Praveen Kumar’s work on studying the mechanical behaviour of materials has earned him various awards, the most recent ones being the Indian National Science Academy Young Scientist Award, 2016, National Academy of Science, India -Young Scientist Platinum Jubilee awards - 2016 and Associate of Indian Academy of Science. In his Thermo-Electro-Mechanical Behaviour Lab at the Department of Materials Engineering, Indian Institute of Science, Prof. Kumar and his students study the effects of size and electric fields on mechanical properties of materials and materials processing.

Fireside chat with Ms. Alyssa Gilbert

The world is definitely getting hotter, thanks to climate change – the topic that is hottest at the moment! What responsibilities do scientific institutes and businesses have, to make this world a cooler place, quite literally? Who can explain this better than Ms. Gilbert, Head of Policy at the Grantham Institute - Climate Change and Environment at Imperial College London! Ms. Gilbert is engaged in connecting relevant research across universities with policy-makers and businesses. In a candid interview during her visit to the Divecha Centre for Climate Change at the Indian Institute of Science, she opens up on her role and its challenges, the opportunities this situation presents, and her opinions on actions that need to be taken in tackling climate change.

IISc Scientists New Discovery Yields a Giant Leap in Graphene Transistor Performance Primary tabs

In a major breakthrough in the field of graphene based electronics, researchers from the Indian Institute of Science, Bangalore, have shown a big jump in understanding the quantum nature of graphene’s interface with outside world. The research team lead by Prof. Mayank Shrivastava (Department of Electronic Systems Engineering), studied how the overlap of atomic orbitals between Carbon and metal atoms affects the graphene-metal interface. The study has enabled them to invent novel techniques to engineer graphene contact that has the lowest recorded resistance to the external world. Their discovery and subsequent invention, while breaking several records – including the one from IBM’s research centre in T. J. Watson, USA – has eventually allowed achieving the highest transistor performance. This work, which is co-authored by PhD student Adil Meersha and co-investigators Prof. Srinivasan Raghavan and Prof. Navakanta Bhat is showcased at International Electron Device Meeting (IEDM), the world’s most competitive platform in the field of electron devices, which mostly showcases technology and fundamental breakthroughs in the field.

Novel Methodology to automatically filter relevant parts from documents

Product designers have the responsibility of ensuring the product they design goes to production without any issues. There are various snippets of “knowledge” available in the form of historic production documents, shop floor records, case studies, etc., both offline and online, that can greatly help get an early insight into potential issues. However, a major drawback is the lack of identifying “knowledge” based on this due to their fragmented distribution. Now, researchers at the Indian Institute of Science, Bangalore, Mr. N. Madhusudanan, Prof. Amaresh Chakrabarti and Prof. B. Gurumoorthy, at the Centre for Product Design and Manufacturinghave developed a method for automatically recovering relevant information from document collections. They validated this methodology in the context of aircraft assembly.