A new study at IISc looks to uncover the secret behind the development of drug resistance in TB causing bacteria by testing the efficacy of various commonly available antibiotics. The researchers have found that a combination of commonly available antibiotics along with Augmentin, fights the development of resistance among TB bacteria. This study might throw light on developing new class of drugs that can help contain the spread of deadly tuberculosis, claim the researchers.
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Though our fight against tuberculosis has a long history, we have not been able to wipe off this bacterial infection from the face of the planet. Even to this day, there are numerous studies all over the world that are trying to find the ‘best’ drug against this killer disease. In a new approach to fight tuberculosis, a recent study has now shone some light on how our body fights Mycobacterium, the causative bacteria of TB. Understanding this mechanism, the researchers say, could open up new vaccines and drugs against TB and help us win the seemingly never ending battle.
But how do bacteria fight against tumours? The answer lies in the environment the tumour creates during its growth. A tumour, by definition, is a mass of cells that have divided in an uncontrolled, abnormal manner without respecting the normal boundaries. Bacteria are known to modulate our immune defence system and strengthen it to fight against tumour cells. Bacteria activate our immune systems and provide an environment for the production of T cells, a type of lymphocyte, that displays greater ability to specifically recognize and act against tumour cells.